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Viagra is specific for which isoform of cGMP phosphodiesterase?(a) PDE2(b) PDE4(c) PDE5(d) PDE8I had been asked this question by my college professor while I was bunking the class.My enquiry is from Cell Signaling and Signal Transduction topic in section Cell Signaling and Signal Transduction of Cell Biology

Answer» RIGHT option is (c) PDE5

Easiest explanation: Cyclic guanosine monophosphate (CGMP) phosphodiesterase is the ENZYME that destroys cyclic guanosine monophosphate. Viagra INHIBITS the particular isoform PDE5 of the enzyme.


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