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The inactive conformation of a G-protein coupled receptor is stabilized by ____________________(a) covalent interactions(b) hydrogen binding(c) non-covalent interactions(d) ionic interactionsI got this question by my school teacher while I was bunking the class.My question is taken from Cell Signaling and Signal Transduction in portion Cell Signaling and Signal Transduction of Cell Biology

Answer»

Right OPTION is (c) non-covalent INTERACTIONS

For explanation: The inactive conformation of the G-protein coupled receptor is stabilized by non-covalent interactions between the residues in the transmembrane alpha helices. Rotation or movements in these LOOPS cause changes in the conformation of cytoplasmic loops.



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