Bringing 2 kinase domains in close contact allows for ___________________(a) trans-autophosphorylation(b) cis-autophosphorylation(c) inactivation of one domain(d) inactivation of both domainsI had been asked this question during a job interview.I want to ask this question from Cell Signaling and Signal Transduction in division Cell Signaling and Signal Transduction of Cell Biology

Bringing 2 kinase domains in close contact allows for ________________

1.	Bringing 2 kinase domains in close contact allows for ___________________(a) trans-autophosphorylation(b) cis-autophosphorylation(c) inactivation of one domain(d) inactivation of both domainsI had been asked this question during a job interview.I want to ask this question from Cell Signaling and Signal Transduction in division Cell Signaling and Signal Transduction of Cell Biology
Answer» Right choice is (a) trans-autophosphorylation For explanation I would say: When TWO DOMAINS of protein-tyrosine kinases come CLOSE, it leads to trans-autophosphorylation in which activity of ONE RECEPTOR of the dimer phosphorylates the tyrosine residue of the other.

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