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Calmodulin has low affinity for _____________(a) magnesium ions(b) iodine(c) non-stimulated cells(d) stimulated cellsThe question was posed to me in a job interview.Enquiry is from Cell Signaling and Signal Transduction in section Cell Signaling and Signal Transduction of Cell Biology

Answer»

The correct choice is (c) non-stimulated cells

For explanation: CALMODULIN contains 4 binding SITES for calcium. It does not have sufficient affinity for Ca^2+ IONS in non-stimulated cells. When the calcium ions concentration increases in response to a stimulus, the ions bind to calmodulin, changing its CONFORMATION.



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