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Class II amino acyl tRNA synthetase transfers the amino acids to the tRNA __________(a) 3’-OH of the A base(b) 3’-OH of the C base(c) 2‘-OH of the A base(d) 2’-OH of the C baseThe question was asked in an interview for job.The question is from TRNA topic in section Gene Expression : Translation of Cytogenetics

Answer»

Correct option is (c) 2‘-OH of the A base

For EXPLANATION I would say: Class II aminoacyl tRNA SYNTHETASE transfers the AMINO acid to the 2’-OH of the tRNA. There is a quick equilibrium between the 2’ and the 3’-OH. On the other hand class I amino acyl tRNA synthetase transfers it to the 3’-OH.


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