1.

In an experiment you delete a part of the 5’ UTR of transferring mRNA, what will be its effect on iron sensitivity?(a) It will be able to sense iron changes better(b) It will not be able to sense the iron changes(c) No change(d) It will have leaky sensitivityThis question was posed to me during an internship interview.The above asked question is from Control of Translation topic in division Gene Expression : Translation of Cytogenetics

Answer»

Correct option is (c) No change

Best EXPLANATION: The IRE, or iron response elements of the transferring gene is located at the 3’ end of the mRNA NEAR the poly A tail. Thus, deletion of a part in 5’end will have no effect at all.



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