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CRM1 is necessary for the export of mRNA.(a) True(b) FalseThis question was posed to me by my college director while I was bunking the class.This key question is from Nuclear Export in chapter Nuclear Export & Post Mendelian Genetics of Cytogenetics

Answer»

The correct option is (b) False

To explain: LMB or leptomycin B treatment prevents the EXPORT by CRM1 as it BINDS to the NES binding site. However, it doesn’t affect export of mRNA which SHOWS that is VIA some other MECHANISM.



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