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Which of these interactions are weak?(a) Ran.GTP-exportin-cargo(b) Ran.GTP-NTF2(c) Ran.GDP-importin(d) Ran-GTP-importinThis question was posed to me in my homework.My query is from Nuclear Export topic in chapter Nuclear Export & Post Mendelian Genetics of Cytogenetics

Answer»

The correct answer is (C) RAN.GDP-importin

Easiest explanation: The HYDROLYSIS of the GTP REDUCES the interaction of Ran with the importin bound to cargo. This results in the release of the cargo into the cytosol.



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