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Endostatin is a ___________________(a) angiogenesis inhibitor(b) angiogenesis promoter(c) transcription factor(d) cell surface receptorI have been asked this question in class test.My enquiry is from Combating Cancer in division Cancer of Cell Biology

Answer»

Correct answer is (a) ANGIOGENESIS inhibitor

The best EXPLANATION: ENDOSTATIN is a NATURALLY occurring inhibitor of angiogenesis – the process of formation of new blood vessels. It is a 20 kilo Dalton fragment of C-terminal of Collagen XVIII, which specifically INHIBITS the proliferation of endothelial cells.



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