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How does Ras oncogene contribute to cancers?(a) It codes for an anti-apoptotic protein, produced in abnormally large amounts(b) It codes for a GTPase switch protein, which in its mutated form cannot be switched off(c) It codes for a transcription factor produced abnormally in large amounts(d) A growth factor that is continually active is encoded in its truncated formThe question was asked by my school principal while I was bunking the class.This interesting question is from Oncogenes, Tumor Suppressor Genes and Programmed Cell Death topic in portion Biosignalling of Biochemistry

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Right CHOICE is (b) It CODES for a GTPase switch protein, which in its mutated FORM cannot be SWITCHED off

The best explanation: Ras oncogene codes for a GTPase switch protein, which in its mutated form cannot be switched off.



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