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IF1 helps in correct placement of the initiation tRNA. How does it do so?(a) By guiding it to P site(b) By binding to A site(c) By dissociating the ribosomal complex(d) By binding to the P siteI got this question in an international level competition.My question is from Initiation topic in chapter Gene Expression : Translation of Cytogenetics

Answer»

Correct choice is (B) By binding to A site

Easy explanation: IF1 binds to the A site of the 30S SUBUNIT so that the 1^st aminoacyl-tRNA can’t sit at the A site. It then sits on the P site i.e. correct position.



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