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In an experiment you charge a tRNA with a wrong base. You allow the mixture to stand for a while. What will you expect to see?(a) Properly charged tRNA(b) Mischarged tRNA(c) Uncharged tRNA(d) Degraded tRNAI have been asked this question by my school principal while I was bunking the class.This is a very interesting question from TRNA in chapter Gene Expression : Translation of Cytogenetics

Answer»

The correct option is (C) UNCHARGED tRNA

Easy explanation: Certain synthetases can cleave the bond between wrong AMINO ACID and the tRNA. This is a type of proofreading mechanism that ENSURES correct amino acid incorporation.



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