In yeast cells, protein transport across the endoplasmic reticulum membrane occurs __________(a) perpendicularly(b) discontinuously(c) co-translationally(d) post-translationallyThis question was addressed to me in an international level competition.Enquiry is from Cytoplasmic Membrane Systems topic in division Cytoplasmic Membrane Systems of Cell Biology

In yeast cells, protein transport across the endoplasmic reticulum mem

1.	In yeast cells, protein transport across the endoplasmic reticulum membrane occurs __________(a) perpendicularly(b) discontinuously(c) co-translationally(d) post-translationallyThis question was addressed to me in an international level competition.Enquiry is from Cytoplasmic Membrane Systems topic in division Cytoplasmic Membrane Systems of Cell Biology
Answer» Correct CHOICE is (d) post-translationally Explanation: Polypeptide is synthesized in the ribosome and if APPROPRIATE signal is present in its C-terminal it moves to the ER membrane during the synthesis, this is called co-translational MOVEMENT. In post-translational movement, the nascent polypeptide reaches the ER membrane after complete synthesis. Unlike mammalian cells post-translational movement of the POLYPEPTIDES is observed in the yeast cells.

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