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‘Niemann^–Pick type C disease’ is caused due to deficiency of a specific ________________(a) protein(b) receptor(c) ligand(d) geneI had been asked this question by my school teacher while I was bunking the class.My query is from Cytoplasmic Membrane Systems topic in division Cytoplasmic Membrane Systems of Cell Biology

Answer»

Right CHOICE is (a) protein

The best explanation: ‘Niemann^–Pick TYPE C disease’ is an inherited disorder in which a protein required to transfer cholesterol out of the lysosomes is lacking. Consequently, cholesterol is ACCUMULATED in these ORGANELLES leading to nerve degeneration.



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