The cysteine residues present in the reduced form in peptides that enter the endoplasmic reticulum lumen are converted into ____________ when they leave the compartment.(a) hydrolyzed bonds(b) hydrophobic bonds(c) disulfide bonds(d) hydrophilic bondsI got this question during an interview.I'm obligated to ask this question of Cytoplasmic Membrane Systems topic in portion Cytoplasmic Membrane Systems of Cell Biology

The cysteine residues present in the reduced form in peptides that ent

1.	The cysteine residues present in the reduced form in peptides that enter the endoplasmic reticulum lumen are converted into ____________ when they leave the compartment.(a) hydrolyzed bonds(b) hydrophobic bonds(c) disulfide bonds(d) hydrophilic bondsI got this question during an interview.I'm obligated to ask this question of Cytoplasmic Membrane Systems topic in portion Cytoplasmic Membrane Systems of Cell Biology
Answer» Right answer is (c) disulfide bonds The BEST I can explain: Disulfide bonds play an important role in the stability of PROTEINS. When the proteins enter ER LUMEN they contain cysteine RESIDUES in the reduced form (-SH) which is converted to oxidized disulfide bonds (-SS-) when they leave the ER, a reaction catalyzed by protein disulfide isomerase (PDI).

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