Inactivation of which of the following leads to detachment of the apoptotic cell?(a) FAK(b) PKB(c) PKC(d) RAF1I had been asked this question by my college director while I was bunking the class.My question is from Cell Signaling and Signal Transduction topic in chapter Cell Signaling and Signal Transduction of Cell Biology

Inactivation of which of the following leads to detachment of the apop

1.	Inactivation of which of the following leads to detachment of the apoptotic cell?(a) FAK(b) PKB(c) PKC(d) RAF1I had been asked this question by my college director while I was bunking the class.My question is from Cell Signaling and Signal Transduction topic in chapter Cell Signaling and Signal Transduction of Cell Biology
Answer» Right option is (a) FAK Easy explanation: The FOCAL ADHESION kinase (FAK) is INACTIVATED by the cleaving action of caspases during apoptosis. Cleavage of FAK leads to detachment of the APOPTOTIC cell from its neighboring cells.

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