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Protein kinase A is ____________(a) Completely inhibited by cyclic AMP(b) Allosterically activated by cyclic AMP(c) Affected by cyclic AMP only under unusual circumstances(d) Activated by covalent binding of cyclic AMPThis question was addressed to me in a job interview.The doubt is from G Protein in portion Biosignalling of Biochemistry

Answer»

Right choice is (b) ALLOSTERICALLY activated by cyclic AMP

The EXPLANATION: Protein kinase A is activated when CAMP allosterically BINDS to a REGULATORY peptide.



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