1.

The active site of chymotrypsin consists of a catalytic triad of which of the following amino acid residues?(a) Serine, histidine and aspartate(b) Serine, histidine and glutamate(c) Threonine, histidine and aspartate(d) Methionine, histidine and aspartateThis question was addressed to me in my homework.The doubt is from Examples Of Enzymatic actions in portion Enzymes, Carbohydrates and Gycobiology of Biochemistry

Answer»

Correct ANSWER is (a) Serine, histidine and ASPARTATE

The EXPLANATION: Aspartate HOLDS the histidine side chain in the correct direction to accept proton from serine.



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