The last proteins to involve in the apoptotic pathway induced by TNF are ______________________(a) caspase-2(b) procaspase-2(c) caspase-8(d) procaspase-8I had been asked this question in exam.Enquiry is from Cell Signaling and Signal Transduction topic in section Cell Signaling and Signal Transduction of Cell Biology

The last proteins to involve in the apoptotic pathway induced by TNF a

1.	The last proteins to involve in the apoptotic pathway induced by TNF are ______________________(a) caspase-2(b) procaspase-2(c) caspase-8(d) procaspase-8I had been asked this question in exam.Enquiry is from Cell Signaling and Signal Transduction topic in section Cell Signaling and Signal Transduction of Cell Biology
Answer» The correct choice is (d) procaspase-8 For explanation I would SAY: The last proteins that get involved in the APOPTOTIC pathway triggered by the tumor necrosis factor are procaspases-8 – the precursors of caspase proteins. Procaspases contain an extra PORTION that must be removed by catalytic action.

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