1.

The Stem loop structures at the 5’ UTR of Ferritin is not ______________(a) Binding to IRE-BP(b) Regulation ferritin level(c) Degraded when unbound(d) Acting as iron sensorI had been asked this question during an interview.The query is from Control of Translation in portion Gene Expression : Translation of Cytogenetics

Answer» RIGHT OPTION is (c) Degraded when unbound

Easiest explanation: The 5’ UTR of the Ferritin can also bind to IRE-BP when IRON concentration is low. In that case the TRANSLATION is prevented. But it is not AU rich so, it is not degraded.


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