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What is the amino acid present in the binding pocket of glutaminyl amino acyl tRNA synthetase?(a) Asp(b) Lys(c) Arg(d) GlnThe question was asked in an interview.The doubt is from TRNA in division Gene Expression : Translation of Cytogenetics

Answer»

The correct CHOICE is (d) Gln

To elaborate: The 3’-OH of the aminoacyl arm of the tRNA enters the BINDING pocket of the synthetase to interact with a Gln AMINO acid correctly placed. This is USED to distinguish it from ASP and Asn.



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