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What is used to regulate translation initiation in eukaryotes?(a) Turnover of mRNA(b) Ubiquitination of ribosome(c) Phosphorylation of IF2(d) Methylation of IF1aI have been asked this question during an interview.Origin of the question is Initiation in portion Gene Expression : Translation of Cytogenetics

Answer» CORRECT choice is (c) Phosphorylation of IF2

To explain I would SAY: Phosphorylation of IF2 prevents it from BINDING to ^f-MettRNA-f-Met, thus it prevents initiation of translation by IF2 bringing the 1^st amino ACID.


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