Which hormone is a major contributor for increasing vascular permeability during inflammation?(a) Histamine(b) Serotonin(c) Bradykinin(d) LeukotrienesThe question was asked in unit test.Asked question is from Drug Addiction and Abuse in portion Local & General Anesthetics, Opioid Analgesics, Drug Addiction and Drug Abuse of Drug Biotechnology

Which hormone is a major contributor for increasing vascular permeabil

1.	Which hormone is a major contributor for increasing vascular permeability during inflammation?(a) Histamine(b) Serotonin(c) Bradykinin(d) LeukotrienesThe question was asked in unit test.Asked question is from Drug Addiction and Abuse in portion Local & General Anesthetics, Opioid Analgesics, Drug Addiction and Drug Abuse of Drug Biotechnology
Answer» The correct choice is (a) HISTAMINE Easiest EXPLANATION: The hormone that acts as a MAJOR contributor for increasing vascular permeability during INFLAMMATION is histamine. In most cases, it is observed that histamine tends to increase vascular permeability by (NO)-dependent vascular dilation and also with increased blood flow.

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