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Which hormone is a major contributor to chemotaxis while inflammation reaction?(a) Histamine(b) Serotonin(c) Prostaglandins(d) LeukotrienesThe question was posed to me by my school teacher while I was bunking the class.The origin of the question is Drug Addiction and Abuse in portion Local & General Anesthetics, Opioid Analgesics, Drug Addiction and Drug Abuse of Drug Biotechnology

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Right option is (c) PROSTAGLANDINS

The best explanation: Prostaglandins released during inflammation reaction PROMOTE edema, causes chemotaxis, leukocyte infiltration and increase vascular permeability, enhance pain producing PROPERTIES of bradykinin. Bradykinin major contributors to symptoms of inflammation. Leukotrienes increase vascular permeability and increase mobilization of ENDOGENOUS mediators of inflammation.



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