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Which of the following are the targets of bacterial toxins botulism and tetanus?(a) Sar1(b) SNAREs(c) Rabs(d) ARF1I got this question in class test.My doubt is from Cytoplasmic Membrane Systems in division Cytoplasmic Membrane Systems of Cell Biology

Answer»

The correct OPTION is (b) SNAREs

Best explanation: SNAREs present on the membranes of synaptic vesicles and PRESYNAPTIC membranes are the only targets of POTENT BACTERIAL toxins; botulism and tetanus. Cleavage of SNAREs by these toxins blocks the release of neurotransmitters and lead to PARALYSIS.



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