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Which of the following factors prevent reassociation of the 40S and 60S subunits when not bound to the mRNA?(a) eIF1 and eIF3(b) eIF2 and eIF3(c) eIF3 and eIF6(d) eIF3 and eIF4This question was posed to me in a national level competition.Enquiry is from Initiation topic in portion Gene Expression : Translation of Cytogenetics

Answer»

Correct OPTION is (c) eIF3 and eIF6

Explanation: While he factor eIF3 binds to the 40S subunit, the other factor eIF6 binds to the 60S subunit and prevent the association of ribosomal SUBUNITS when not bound to MRNA.



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