1.

Which of the following is also termed as a death receptor?(a) TNFR1(b) TNFR2(c) TNFR3(d) TNFR4The question was posed to me in examination.The origin of the question is Cell Signaling and Signal Transduction topic in section Cell Signaling and Signal Transduction of Cell Biology

Answer»

The CORRECT choice is (a) TNFR1

To explain I would say: DEATH receptors are so called because of the presence of a death domain which is RESPONSIBLE for killing an INFECTED CELL. TNFR1 is one such example. It plays an important role in induced apoptosis.



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