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Which of the following takes place due to phosphorylation of isocitrate dehydrogenase?(a) Inhibits the binding of citrate at active site(b) Degrades the enzyme(c) Enhances the substrate-binding affinity(d) No reactionI got this question during an online interview.My question is from Regulatory Enzymes in chapter Enzymes, Carbohydrates and Gycobiology of Biochemistry |
Answer» RIGHT option is (a) INHIBITS the BINDING of citrate at active site For explanation I would say: The electrostatic repulsion by the PHOSPHORYL group inhibits the binding of citrate at active site. |
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