1.

Which one of the following has GEF activity?(a) eIF1A(b) eIF2(c) eIF2B(d) eIF5This question was posed to me in examination.My doubt is from Initiation in portion Gene Expression : Translation of Cytogenetics

Answer»

Correct answer is (c) eIF2B

For explanation: The factor eIF2B is a GUANOSINE nucleotide EXCHANGE Factor or GEF. It exchanges the GDP BOUND to EIF2 to GTP so that it can then bind to the aminoacyl tRNA.



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