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Which poly a tail binding protein helps in the initiation of translation?(a) CPSF(b) PAP(c) PABP1(d) PABP2This question was posed to me during a job interview.My question is based upon Initiation topic in chapter Gene Expression : Translation of Cytogenetics

Answer»

The correct option is (d) PABP2

Explanation: PABP2 can bind the POLY a tail to the eIF4E through the MEDIATOR eIF4G. This increases the ASSOCIATION of the 40S subunit to the 5’ end of the mRNA thus increasing translation.



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