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Which state of the ‘Rabs’ is the active state?(a) GDP-bound(b) GTP-bound(c) Membrane-bound(d) Lipid-boundI had been asked this question during an interview for a job.The above asked question is from Cytoplasmic Membrane Systems topic in section Cytoplasmic Membrane Systems of Cell Biology

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Right answer is (b) GTP-bound

Best EXPLANATION: The ‘RABS’ are encoded by over 60 diverse genes in humans and they cycle between two states; GTP-bound ACTIVE state and GDP-bound inactive state.



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