Why the pain can be felt during inflammation?(a) Local blood vessel dilation(b) Influx of plasma proteins(c) Release of enzymes and increased of tissue pressure(d) Influx of phagocytic cellsThis question was posed to me during an online interview.This interesting question is from Drug Addiction and Abuse in portion Local & General Anesthetics, Opioid Analgesics, Drug Addiction and Drug Abuse of Drug Biotechnology

Why the pain can be felt during inflammation?(a) Local blood vessel di

1.	Why the pain can be felt during inflammation?(a) Local blood vessel dilation(b) Influx of plasma proteins(c) Release of enzymes and increased of tissue pressure(d) Influx of phagocytic cellsThis question was posed to me during an online interview.This interesting question is from Drug Addiction and Abuse in portion Local & General Anesthetics, Opioid Analgesics, Drug Addiction and Drug Abuse of Drug Biotechnology
Answer» Correct option is (c) Release of enzymes and increased of tissue PRESSURE The explanation is: The pain is due to local release of enzymes and increased tissue pressure. Bradykinin is the most important pain mediator in an inflammation reaction. The REDNESS and heat is due to the local blood vessel dilation. The swelling is due to the INFLUX of plasma proteins and phagocytic CELLS into the tissue spaces. These are the four signs of inflammation which can be seen in a HUMAN body.

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