

InterviewSolution
This section includes InterviewSolutions, each offering curated multiple-choice questions to sharpen your knowledge and support exam preparation. Choose a topic below to get started.
51. |
During Strisinger’s model, what happens?(a) The Ribosome slips which causes duplication(b) Parent strand slippage polymerase(c) Daughter strand slippage polymerase(d) The polymerase back tracks and resynthesizesI had been asked this question during an interview.This is a very interesting question from Chromosomal Abnormalities : Duplication in division Chromosomal Basis of Inheritance of Cytogenetics |
Answer» Right answer is (C) DAUGHTER strand slippage polymerase |
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52. |
Choose the wrong one out for insertion sequence.(a) Insertion sequences are transposons(b) Insertion sequences range from 5kb to 30kb(c) Insertion sequences only carry genes for their transposition(d) Insertion sequences have terminal IRI have been asked this question in an internship interview.Question is taken from Chromosomal Abnormalities : Translocation in chapter Chromosomal Basis of Inheritance of Cytogenetics |
Answer» Correct option is (b) Insertion sequences range from 5kb to 30kb |
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53. |
______________ inversions reduce crossing over in ______________(a) Paracentric, Heterozygous(b) Pericentric, Heterozygous(c) Paracentric, homozygous(d) Pericentric homozygousThe question was posed to me by my college professor while I was bunking the class.The question is from Chromosomal Abnormality : Inversion topic in portion Chromosomal Basis of Inheritance of Cytogenetics |
Answer» Correct option is (b) PERICENTRIC, Heterozygous |
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54. |
Translocation in plants was discovered by_____________(a) Stern(b) Barbara McClintok(c) Sutton and Boveri(d) MorganI have been asked this question during an online interview.Origin of the question is Chromosomal Abnormalities : Translocation topic in division Chromosomal Basis of Inheritance of Cytogenetics |
Answer» CORRECT choice is (b) Barbara McClintok The explanation is: Barbara McClintok 1st OBSERVED translocation in maize. Sutton and Boveri gave the chromosomal THEORY of INHERITANCE. |
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55. |
The chromosomal theory of inheritance was proposed by ____________(a) Mendel(b) Watson and Crick(c) Darwin(d) Sutton and BoveriThis question was posed to me in an online interview.My question is from Chromosomal Theory of Inheritance in chapter Chromosomal Basis of Inheritance of Cytogenetics |
Answer» The CORRECT answer is (d) Sutton and Boveri |
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56. |
At what maternal age the probability of having a child with Down’s syndrome is increased drastically?(a) 25(b) 30(c) 35(d) 45This question was addressed to me in unit test.I want to ask this question from Chromosomal Abnormalities : Aneuploidy topic in portion Chromosomal Basis of Inheritance of Cytogenetics |
Answer» The correct OPTION is (c) 35 |
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57. |
A non-disjunction in the 1^st phase of meiosis will lead to ______________(a) Monosomy(b) Nullysomy(c) Disomy(d) TrtrasomyThis question was addressed to me at a job interview.I'd like to ask this question from Chromosomal Abnormalities : Aneuploidy topic in portion Chromosomal Basis of Inheritance of Cytogenetics |
Answer» The correct option is (b) Nullysomy |
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58. |
Patau syndrome is a result of which of the following?(a) Non-disjunction of sex chromosome in female(b) Non- disjunction of sex chromosome in male(c) Non-disjunction of chromosome 21(d) Non-disjunction of chromosome 13This question was posed to me in examination.The question is from Chromosomal Abnormalities : Aneuploidy topic in chapter Chromosomal Basis of Inheritance of Cytogenetics |
Answer» Correct OPTION is (d) Non-disjunction of chromosome 13 |
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59. |
Normal wheat Triticum aestivum is ___________(a) Monoploid(b) Tetraploid(c) Pentaploid(d) HexaploidI got this question during an interview for a job.Question is taken from Chromosomal Abnormalities : Euploidy in chapter Chromosomal Basis of Inheritance of Cytogenetics |
Answer» Correct choice is (d) Hexaploid |
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60. |
Duplication of Vermillion eye colour gene leads to the expression of the mutant phenotype. Which of the following can lead to normal phenotype with this duplication present?(a) Reverse tandem duplication(b) Duplication of normal eye colour gene(c) Deletion of both the Vermillion gene(d) Translocation of Vermillion gene to another chromosomeI have been asked this question at a job interview.This intriguing question originated from Chromosomal Abnormalities : Duplication topic in chapter Chromosomal Basis of Inheritance of Cytogenetics |
Answer» The correct OPTION is (b) Duplication of normal eye colour gene |
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61. |
Non-autonomous transposons can’t transpose. State whether the statement is true or false.(a) True(b) FalseI have been asked this question by my college professor while I was bunking the class.Enquiry is from Chromosomal Abnormalities : Translocation in section Chromosomal Basis of Inheritance of Cytogenetics |
Answer» CORRECT ANSWER is (b) False To explain I would say: Non-autonomous transposons LACK the RECOMBINASE that aids in transposition. However, they can transpose with the help of the recombinase from another trasposon. |
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62. |
Which of the following is a result of reciprocal translocation?(a) Burkitt’s lymphpma(b) Trychothiodystrophy(c) Thalassemia(d) Cockyne’s syndromeI have been asked this question in an international level competition.My query is from Chromosomal Abnormalities : Translocation in section Chromosomal Basis of Inheritance of Cytogenetics |
Answer» CORRECT answer is (a) Burkitt’s lymphpma Best explanation: Burkitt’s lymphoma is a result of reciprocal translocation between chromosome 8 and 14 of HUMAN GENOME. Trichothiodystrophy is a defect in NER. |
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63. |
Which of the following can result from non-disjunction?(a) XY and XO(b) YY and XY(c) X and Y(d) XY and XXYI have been asked this question in exam.My question is based upon Chromosomal Theory of Inheritance in division Chromosomal Basis of Inheritance of Cytogenetics |
Answer» CORRECT choice is (a) XY and XO To explain: Non-disjunction in the male will produce XY and XO RESPECTIVELY. The other options are not suitable results of non-disjunction. In this case some part having XY will develop a male character with the parts with XO will have FEMALE characters. |
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64. |
You hybridize two cells one of which carries a deletion mutation on chromosome 1. What will you expect to observe?(a) Buckling of chromatin of 1^st cell(b) Buckling of chromatin of 2^nd cell(c) Twisting and loop formation between the two chromatins(d) No observable differenceThe question was asked in class test.Question is from Chromosomal Abnormalities : Deletion in division Chromosomal Basis of Inheritance of Cytogenetics |
Answer» Right OPTION is (b) Buckling of chromatin of 2^nd cell |
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65. |
If the genes are located in a chromosome as A—B—C—D—E—O—-T. Which of the gene pairs will have least probability of being inherited together?(a) C and D(b) A and T(c) A and B(d) O and TThis question was posed to me during an interview for a job.This interesting question is from Chromosomal Theory of Inheritance in portion Chromosomal Basis of Inheritance of Cytogenetics |
Answer» The correct answer is (b) A and T |
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66. |
How will you recognize a terminal deletion from breakage and loss at the terminal end?(a) Indistinguishable(b) Terminal break will lead to shorter chromosome than that due to chunk deletion(c) Terminal break will be sticky(d) Deletion will be recognized by trans factorsThe question was asked during an interview for a job.My doubt stems from Chromosomal Abnormalities : Deletion in chapter Chromosomal Basis of Inheritance of Cytogenetics |
Answer» The CORRECT option is (c) TERMINAL break will be STICKY |
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67. |
In Drosophila Crossing over in paracentric region is lethal and leads to cross-over suppression. This leads to reduction in fertility.(a) True(b) FalseThis question was addressed to me in an interview for job.My enquiry is from Chromosomal Abnormality : Inversion in chapter Chromosomal Basis of Inheritance of Cytogenetics |
Answer» The correct ANSWER is (b) False |
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68. |
Which of the following could result in homologous chromosomes moving to the same pole after anaphase 1?(a) Doubling(b) Inversion(c) Breaking(d) TranslocationI have been asked this question during a job interview.Enquiry is from Chromosomal Abnormalities : Translocation topic in chapter Chromosomal Basis of Inheritance of Cytogenetics |
Answer» Correct option is (d) Translocation |
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69. |
Aneuploidy is usually deleterious as _________________(a) Chromosomal pairing is hampered(b) Gene balance is disrupted(c) Size of individual may vary(d) Chromosomal disintegration is increasedI got this question in an internship interview.My question comes from Chromosomal Abnormalities : Aneuploidy in section Chromosomal Basis of Inheritance of Cytogenetics |
Answer» The correct choice is (b) Gene BALANCE is disrupted |
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70. |
A male ant is _______________(a) Polyploid(b) Triploid(c) Diploid(d) MonoploidI have been asked this question at a job interview.The above asked question is from Chromosomal Abnormalities : Euploidy topic in chapter Chromosomal Basis of Inheritance of Cytogenetics |
Answer» Correct choice is (d) Monoploid |
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71. |
Long pericentric inversions generally don’t act as cross over suppressors. Why?(a) Long stretches of DNA recombination not recognized(b) Mechanism is different for short and long inversions(c) Two events of crossing over take place(d) Cross over product in this is viableI had been asked this question in my homework.I'd like to ask this question from Chromosomal Abnormality : Inversion topic in division Chromosomal Basis of Inheritance of Cytogenetics |
Answer» The correct option is (c) Two events of crossing over take place |
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72. |
Which of the following is not true about conservative transposition?(a) It creates direct repeat sequences on either side(b) It is Copy-Paste mechanism(c) Transesterification reaction takes place(d) Class II transposons have this mechanismI have been asked this question by my college professor while I was bunking the class.This interesting question is from Chromosomal Abnormalities : Translocation topic in division Chromosomal Basis of Inheritance of Cytogenetics |
Answer» Right choice is (b) It is Copy-Paste MECHANISM |
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73. |
Which of the following case of duplication involves more than one chromosome?(a) Tandem duplication(b) Reverse tandem duplication(c) Displaced(d) TransposedThis question was posed to me in an internship interview.This interesting question is from Chromosomal Abnormalities : Duplication in chapter Chromosomal Basis of Inheritance of Cytogenetics |
Answer» RIGHT option is (d) Transposed For EXPLANATION: In transposed the SEGMENT could be passed to another homologous chromosome or extra chromosome with a centromere. However, TANDEM, revere tandem and displaced occurs WITHIN the same chromosome. |
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74. |
Which of the following is an example of inversion?(a) Chromosome 22 and 9(b) Chromosome 8(c) Chromosome 14(d) Chromosome 3This question was posed to me in a national level competition.This question is from Chromosomal Abnormality : Inversion in chapter Chromosomal Basis of Inheritance of Cytogenetics |
Answer» Correct ANSWER is (d) Chromosome 3 |
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75. |
Which of the segregation of translocated chromosome will result in non- lethal gamete?(a) Homologous chromosomes moving to same pole(b) Alternate segregation(c) Adjacent with the homologous chromosomes moving to same pole(d) Adjacent with homologous chromosomes moving to different poleThe question was posed to me by my college director while I was bunking the class.My question is taken from Chromosomal Abnormalities : Translocation in section Chromosomal Basis of Inheritance of Cytogenetics |
Answer» The correct OPTION is (b) Alternate SEGREGATION |
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76. |
If there is a non-disjunction in the X chromosome, the progeny being XXY, what will be the constitution of the chromosome(s) in the gamete?(a) X and Y(b) X and XY(c) XX and Y(d) XXY with no separationI had been asked this question in semester exam.Question is from Chromosomal Theory of Inheritance topic in division Chromosomal Basis of Inheritance of Cytogenetics |
Answer» Right choice is (b) X and XY |
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77. |
Transposition doesn’t require much sequence homology between two genetic molecules, based on this hey can help in _____________(a) Homologous DSB repair(b) Non-homologous end joining(c) Site-specific recombination(d) Homologous recombinationThe question was posed to me during an interview for a job.This intriguing question comes from Chromosomal Abnormalities : Translocation in portion Chromosomal Basis of Inheritance of Cytogenetics |
Answer» Correct answer is (c) Site-specific RECOMBINATION |
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78. |
Which of the following doesn’t agree with the chromosomal theory of inheritance?(a) The genes are located on the chromosome(b) The genes on the same chromosome are always passed together(c) The genes are located linearly on the chromosomes(d) The distance between two genes can be mappedThe question was asked in examination.My doubt is from Chromosomal Theory of Inheritance in division Chromosomal Basis of Inheritance of Cytogenetics |
Answer» Correct choice is (b) The genes on the same chromosome are always passed TOGETHER |
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79. |
If an organism has 14 chromosomes, the number of chromosome generated by nullisomy will be_____________________(a) 15(b) 7(c) 13(d) 12I have been asked this question in semester exam.This interesting question is from Chromosomal Abnormalities : Aneuploidy topic in section Chromosomal Basis of Inheritance of Cytogenetics |
Answer» Correct OPTION is (d) 12 |
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80. |
Colchicine is used to cause______________(a) Mitotic non-disjunction(b) Meiotic non-disjunction(c) Mitotic disjunction(d) Meiotic disjunctionI had been asked this question in an internship interview.The above asked question is from Chromosomal Abnormalities : Euploidy in section Chromosomal Basis of Inheritance of Cytogenetics |
Answer» The correct CHOICE is (a) Mitotic non-disjunction |
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81. |
Which of the following will be sterile?(a) Tetraploid(b) Triploid(c) Diploid(d) MonoploidI got this question in an online interview.My doubt stems from Chromosomal Abnormalities : Euploidy in chapter Chromosomal Basis of Inheritance of Cytogenetics |
Answer» | |
82. |
Euploidy is a chromosomal variation in ______________________(a) Size(b) Position of genes(c) Number(d) StructureI have been asked this question in examination.The doubt is from Chromosomal Abnormalities : Euploidy topic in section Chromosomal Basis of Inheritance of Cytogenetics |
Answer» Right option is (C) NUMBER |
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83. |
Which of the following will have the highest number of eye facete?(a) Ultra bar female Drosophila(b) Heterozygous Bar male Drosophila(c) Heterozygous Bar female Drosophila(d) Homozygous bar FemaleI had been asked this question by my school teacher while I was bunking the class.My query is from Chromosomal Abnormalities : Duplication in chapter Chromosomal Basis of Inheritance of Cytogenetics |
Answer» Correct answer is (C) Heterozygous BAR FEMALE Drosophila |
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84. |
Positive effect Variegations can lead to___________(a) Translocation(b) Over expression(c) Under expression(d) SuppressionThis question was posed to me in an online quiz.This is a very interesting question from Chromosomal Abnormalities : Translocation topic in portion Chromosomal Basis of Inheritance of Cytogenetics |
Answer» CORRECT choice is (d) Suppression To explain I would say: DUE to translocation some part of the gene can get transcribed to a POSITION NEAR heterochromatin REGION. This will suppress the otherwise expressed gene. |
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85. |
If you cross a white eyed female drosophila with a red eyed male drosophila, what will be the colour of eyes for their male and female offspring?(a) Both red eyed(b) Both white eyed(c) Red eyed daughter and white eyed son(d) Red eyed son and white eyed daughterThis question was posed to me at a job interview.I need to ask this question from Chromosomal Theory of Inheritance topic in chapter Chromosomal Basis of Inheritance of Cytogenetics |
Answer» Correct answer is (c) Red EYED daughter and white eyed son |
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