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Pre-replication complex is necessary to initiate replication. It assembles in______________(a) Late Anaphase(b) G1 phase(c) S phase(d) Early AnaphaseThe question was posed to me in quiz.My doubt stems from DNA Replication Eukaryotes topic in portion DNA Replication of Cytogenetics

Answer»

Correct answer is (B) G1 PHASE

Easy explanation: Pre-replication complex assembles on ORC in G1 phase. It is triggered in S phase when no new Pre-RC ASSEMBLY TAKES place. Even during early Anaphase and late Anaphase this complex assembly is PREVENTED.



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