1.

You are given a DNA fragment with a CBD lesion. Which polymerase(s) will you use to replicate this fragment without taking care of the error?(a) ζ (zeta), η (eta)(b) η (eta), ) θ (theta)(c) θ (theta), κ (kappa)(d) κ (kappa),θ (theta)The question was asked during an interview.I would like to ask this question from DNA Replication Eukaryotes topic in section DNA Replication of Cytogenetics

Answer»

The correct OPTION is (b) η (eta), ) θ (theta)

The best I can explain: Eta introduces two random BASE against the lesion say AA or TT.However, it is very ERROR prone and requires zeta to carry out the remaining REPLICATION. Kappa and theta also participate in repair but by other WAYS.



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