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What is the first reaction of the pentose phosphate pathway?(a) Oxidation of glucose 6-phosphate to 6-phosphoglucono-δ-lactone(b) Oxidation of 6-phosphogluconate to ketopentose ribulose 5-phosphate(c) Reduction of 6-phosphoglucono-δ-lactone to glucose 6-phosphate(d) Reduction of ketopentose ribulose 5-phosphate to 6-phosphogluconateThis question was addressed to me in an interview for job.This question is from Pentose Phosphate Pathway of Glucose Oxidation in section Principles of Bioenergetics and Glycolysis of Biochemistry

Answer»

The correct answer is (a) Oxidation of glucose 6-phosphate to 6-phosphoglucono-δ-lactone

For explanation: The FIRST reaction of the PENTOSE phosphate PATHWAY is the oxidation of glucose 6-phosphate to 6-phosphoglucono-δ-lactone by glucose 6-phosphate DEHYDROGENASE.



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