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Whenever the cell’s ATP supply is depleted, which of the following enzyme’s activity is increased?(a) Hexokinase(b) Pyruvate kinase(c) Glucokinase(d) Phosphofructokinase-1I have been asked this question during a job interview.I'd like to ask this question from Glycolysis topic in section Principles of Bioenergetics and Glycolysis of Biochemistry

Answer»

The correct CHOICE is (d) Phosphofructokinase-1

The best I can explain: Phosphofructokinase-1 is a REGULATORY enzyme; it is the major point of REGULATION in glycolysis. Its ACTIVITY is increased whenever the cell’s ATP supply is depleted.



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