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Which of the following are the structural motifs that mediate protein-protein interactions?(a) Leucine zipper and basic helix-loop-helix(b) Homeodomain(c) Zinc finger(d) Helix-turn-helixThe question was asked in a job interview.Question is from Principles of Gene Regulation in section Regulation of Gene Expression and Miscellaneous of Biochemistry

Answer»

The correct choice is (a) Leucine zipper and basic helix-loop-helix

The explanation: REGULATORY proteins contain DOMAINS not only for DNA binding but also for protein-protein interactions. Homeodomain, ZINC FINGER and helix-turn-helix are DNA-binding domains.



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