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Proteins tagged with mannose 6-phosphate are transported to ____________(a) Golgi complex(b) Mitochondria(c) Lysosome(d) NucleusThe question was asked by my college professor while I was bunking the class.My question is from Protein Targeting and Degradation topic in portion DNA, RNA and Protein Metabolism of Biochemistry

Answer»

Correct answer is (c) Lysosome

To EXPLAIN: The presence of ONE or more mannose 6-phosphate residues in its N-linked oligosaccharide is the STRUCTURAL signal that targets the protein to LYSOSOMES.



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