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Which of the following enzymes remove supercoiling in replicating DNA ahead of the replication fork?(a) DNA polymerases(b) Helicases(c) Primases(d) TopoisomerasesThis question was addressed to me by my school principal while I was bunking the class.Question is from DNA Replication in division DNA, RNA and Protein Metabolism of Biochemistry

Answer»

Correct answer is (d) TOPOISOMERASES

To explain: Strand separation creates topological STRESS in the helical DNA STRUCTURE which is RELIEVED by the action of topoisomerases.



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